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BMS1021 - Cells, tissues and organisms - S1 2025

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Use the picture below to answer the following questions.

Image failed to load: Teaching/Biol1011/GFPmChe_question2.png

You want to study three genes, so you create three fusion proteins. The first gene (gene1) is fused to green fluorescent protein (GFP), the second gene (gene2) is fused to red fluorescent protein (RFP) and third protein (gene3) is fused to a cyan fluorescent protein (CFP). You study a cross section view of a single cell under the microscope.

What type of protein is encoded by gene1?

You modify gene1 so that its protein product is not targeted to the rough endoplasmic reticulum (ER), but is still translated by ribosomes. What will be the final destination of the protein produced by this modified gene?

You express your gene2/RFP fusion gene inside several types of human cell. You find that this protein is most abundant in a muscle cell - the whole cell appears to be red. What organelle is the product of gene2 targeted to?

You are puzzled when you look at the gene3 fusion product - when you study the cell over a period of time, you see that the cyan fusion protein is produced, transported to an organelle, but then that the colour slowly disappears over time. What organelle do you think the gene3/CFP fusion protein is being targeted to?

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When calculating Surface Area to Volume ratios (SA:V), the following formulas are used:

Sphere:

    • Surface area = 4πr2
    • Volume = 4/3πr3
    • Where π = 3.14 and r = radius of the sphere
Cube:

    • Surface area = 6 x (length x depth)
    • Volume = length x depth x height

You have been given two cell samples:

    • Cell A is a spherical cell with a radius of 5 µm.
    • Cell B is a cube-shaped cell with a length, depth, and height of 10 µm.

a) What is the SA:V of Cell A?

 : 1

Input numerical answer to one decimal place.

b) What is the SA:V of Cell B?

 : 1

Input numerical answer to one decimal place.

c) Based on the above calculations, which cell (A or B) would most efficiently transport substances across the cell membrane?

Please answer all parts of the question.
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Please submit the scientific drawing of your cell here. It must be submitted in PDF format (.pdf).

Your drawing will be assessed on the following:

    • How well it conforms to the standard conventions of scientific drawings (as outlined in your lab notes)
    • Inclusion of all required components
    • Accuracy and clarity of the drawn components
    • Legibility of any accompanying text.

Your submission must be a photograph of a hand-drawn cell in pencil on plain white paper. Drawings that have been generated electronically will not be accepted and will receive zero marks.

Drawing that conforms to all scientific conventions = 9 marks

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Environmental Condition 3:

The environment contains predators that a cell must evade in order to survive.

Which ONE of the following options describes a single-celled organism best adapted to this environmental condition, together with an accurate justification?

0%
0%
100%
0%
0%
0%
0%
0%
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Environmental Condition 2:

The environment contains high levels of hydrogen peroxide which is toxic to the cell.

Which ONE of the following options describes a single-celled organism best adapted to this environmental condition, together with an accurate justification?

0%
0%
0%
0%
0%
0%
33%
67%
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Environmental Condition 1:

There is no land or bodies of saltwater on the planet. The entire planet’s habitat is freshwater.

Which ONE of the following options describes a single-celled organism best adapted to this environmental condition, together with an accurate justification?

0%
0%
0%
0%
0%
100%
0%
0%
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Use the picture below to answer the following questions.

Image failed to load: Teaching/Biol1011/GFPmChe_question2.png

You want to study three genes, so you create three fusion proteins. The first gene (gene1) is fused to green fluorescent protein (GFP), the second gene (gene2) is fused to red fluorescent protein (RFP) and third protein (gene3) is fused to a cyan fluorescent protein (CFP). You study a cross section view of a single cell under the microscope.

What type of protein is encoded by gene1?

You modify gene1 so that its protein product is not targeted to the rough endoplasmic reticulum (ER), but is still translated by ribosomes. What will be the final destination of the protein produced by this modified gene?

You express your gene2/RFP fusion gene inside several types of human cell. You find that this protein is most abundant in a muscle cell - the whole cell appears to be red. What organelle is the product of gene2 targeted to?

You are puzzled when you look at the gene3 fusion product - when you study the cell over a period of time, you see that the cyan fusion protein is produced, transported to an organelle, but then that the colour slowly disappears over time. What organelle do you think the gene3/CFP fusion protein is being targeted to?

Please answer all parts of the question.
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Below is a dichotomous key classifying each of the specimens A-H.

Image failed to load

Following the key and using the information collected in your lab results sheet, indicate which specimen is identified by each numbered label (1-8).

Note: each specimen should only be used once.

1. 

2. 

3. 

4. 

5. 

6. 

7. 

8. 

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Use the picture below to answer the following questions.

Image failed to load: Teaching/Biol1011/GFPmChe_question2.png

You want to study three genes, so you create three fusion proteins. The first gene (gene1) is fused to green fluorescent protein (GFP), the second gene (gene2) is fused to red fluorescent protein (RFP) and third protein (gene3) is fused to a cyan fluorescent protein (CFP). You study a cross section view of a single cell under the microscope.

What type of protein is encoded by gene1?

You modify gene1 so that its protein product is not targeted to the rough endoplasmic reticulum (ER), but is still translated by ribosomes. What will be the final destination of the protein produced by this modified gene?

You express your gene2/RFP fusion gene inside several types of human cell. You find that this protein is most abundant in a muscle cell - the whole cell appears to be red. What organelle is the product of gene2 targeted to?

You are puzzled when you look at the gene3 fusion product - when you study the cell over a period of time, you see that the cyan fusion protein is produced, transported to an organelle, but then that the colour slowly disappears over time. What organelle do you think the gene3/CFP fusion protein is being targeted to?

Переглянути це питання
When calculating Surface Area to Volume ratios (SA:V), the following formulas are used:

Sphere:

    • Surface area = 4πr2
    • Volume = 4/3πr3
    • Where π = 3.14 and r = radius of the sphere
Cube:

    • Surface area = 6 x (length x depth)
    • Volume = length x depth x height

You have been given two cell samples:

    • Cell A is a spherical cell with a radius of 5 µm.
    • Cell B is a cube-shaped cell with a length, depth, and height of 10 µm.

a) What is the SA:V of Cell A?

 : 1

Input numerical answer to one decimal place.

b) What is the SA:V of Cell B?

 : 1

Input numerical answer to one decimal place.

c) Based on the above calculations, which cell (A or B) would most efficiently transport substances across the cell membrane?

Переглянути це питання

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