A 62-year-old man has a red, warm, painful lesion on his skin that

extends across his calf from the popliteal fossa to the ankle. This condition

is diagnosed as cellulitis, a bacterial infection of the deeper layers of the

skin. The red colour, increased temperature, and pain of the affected area are

due to an inflammatory response to the infection. In the patient, this

inflammatory reaction is largely caused by the release of pro-inflammatory

substances from the cells of the immune system, which are abundant in the

connective tissue. Which of the following cell types are involved?

A student is reviewing how connective tissue structure correlates to function of an organ. Which of the following might be the source of the tissue in the figure below?

A 16-year-old boy

fell and injured his knee during the school’s recent game. A physical

examination showed strong instability of the knee and an MRI examination

confirmed a rupture of the anterior cruciate ligament. What type of tissue is

the anterior cruciate ligament?

A 6-year-old boy

presents with special symptoms – joint stiffness, corneal opacity, heart valve abnormality,

and worsening hearing impairment. After a complex diagnosis, the final is the type I mucopolysaccharidosis. Mucopolysaccharidoses are

hereditary disorders of the activity of lysosomal enzymes, whose role in a

healthy organism is the natural breakdown of glycosaminoglycans

(mucopolysaccharides). During these diseases, glycosaminoglycans accumulate

inside these lysosomes. What are glycosaminoglycans?

The researcher is

concerned with obesity and its effect on the human endocrine system. Leptin as

one of the hormones of adipose tissue normally induces satiety and suppresses

hunger in the hypothalamus. It regulates energy output and intake to a large

extent by influencing feeding behaviour, appetite, hunger, and energy

metabolism. Because its circulating amount corresponds to the amount of adipose

tissue in the body, it provides feedback information to the brain about the

state of energy stores. In obese people, there is a persistently elevated level

of this hormone, called hyperleptinemia, and therefore the body of obese people

develops resistance to it. Select from the pictures the tissue that produces

leptin.

An investigator is studying collagen synthesis in human fibroblast

cells. Using a fluorescent tag, α-collagen chains are identified and

then monitored as they travel through the rough endoplasmic reticulum, the

Golgi apparatus, and eventually into the extracellular space. Which of the

following steps in collagen synthesis occurs extracellularly?

Match the correct histological type of connective tissue proper with the microphoto.

A 7-week-old infant

is brought to the emergency department for severe hypothermia. Such a small

child does not have enough muscle mass to produce heat through muscle tremors,

and at the same time, his body has a large surface area causing easier heat

loss. Newborns and infants have a special way of producing heat through

non-shivering thermogenesis using brown adipose tissue. What does the basic

structure of this tissue look like?

A student is reviewing how connective tissue structure correlates to function of an organ. Which of the following might be the source of the tissue in the figure below?