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A 12 year old boy comes to chest clinic with an episode of chest tightness and ...

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A 12 year old boy comes to chest clinic with an episode of chest tightness and wheezes.  His mother tells the pulmonogist  that he his nebulizer sessions  improve  his chest condition. The pulmonogist suspects that the boy has bronchial asthma.

What is the single best investigation  to confirm that the boy has bronchial asthma?

 

 

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