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PHY2011 - Neuroscience of communication, sensory and control systems - S1 2025

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A cat soleus muscle is composed of 32202 muscle fibres. Assume that the force developed by a motor unit is proportional to the number of muscle fibres it contains. If the maximum tetanic force developed by the soleus muscle is 29.3 Newtons (N), calculate the number of muscle fibres in the smallest motor unit, if this motor unit develops a force of 34 milliNewtons (mN).

Answer in whole numbers, with no decimal places.

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A large motor neuron with a diameter of 18 m

m has a conduction velocity of 76 m/sec. If its length from the spinal cord to the muscle it innervates is 1.1m, how long would it take an AP at the cell body (in the spinal cord) to reach the muscle ?

Answer in seconds to 3 decimal places.

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A myelinated nerve fibre has a conduction velocity of 80 m/sec and internode lengths of 1.2 mm.

How long does it take an action potential to spread from one node of Ranvier to the next ?

Answer in milliseconds to 3 decimal places.

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The nerve supplying a cat soleus muscle consists of 511 myelinated axons, of which 66% are motor. Of these motor axons, 31% supply muscle spindles and, therefore, do not contribute to the force developed by the contracting muscle.

Of how many motor units is this soleus muscle composed ?

Answer in whole numbers, with no decimal places.

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A Beaker is divided into two chambers, A and B, by a semi-permeable membrane lying across the middle of the beaker.

Chamber A contains the following concentration of ions:

{Na+} = 58 mM,, {K+} = 140 mM, {Cl-} = 100 mM, {A-} = 106 mM

Chamber B contains the following concentration of ions:

{Na+} = 200 mM,, {K+} = 18 mM, {Cl-} = 50 mM, {A-} = 152 mM

If the membrane is permeable only to K

+

, what is the transmembrane potential difference of Chamber A relative to Chamber B?

Answer in whole numbers, with no decimal places. In your answer give only the numerical (asbolute) value - i.e., ignore the sign of the answer.

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A myelinated nerve fiber has a diameter of 10 um and a conduction velocity of 60 m/sec. What would you expect to be the diameter (in u

m) of a fibre which has a conduction velocity of 102 m/sec ?

Answer in whole numbers, with no decimal places.

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A Beaker is divided into two chambers, A and B, by a semi-permeable membrane lying across the middle of the beaker. Chamber A contains the following concentration of ions:

{Na+} = 49 mM, {K+} = 100 mM, {Cl-} = 110 mM

Chamber B contains the following concentration of ions:

{Na+} = 111 mM, {K+} = 10 mM, {Cl-} = 110 mM

If the membrane is permeable only to Na+, what is the transmembrane potential difference of Chamber A with respect to Chamber B?

Answer in whole numbers, with no decimal places. In your answer give only the numerical (asbolute) value - i.e., ignore the sign of the answer.

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The number of millimoles of NaOH needed to make 720 ml of a 0.13 M solution is?

The formula weight of NaOH is 40.

Answer to 2 decimal places. Do not enter units in your answer.
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What is the percentage concentration of a solution 0.9 M NaCl solution.

The formula weight of NaCl is 58.44.

Answer to 2 decimal places. Do not enter units in your answer.
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What is the concentration as %w/v of a solution which contains 447 millimoles per litre of NaCl

The formula weight of NaCl is 58.44.

Answer to 3 decimal places. Do not enter units in your answer.
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