Use lay / simple language to describe 4-5 different symptoms of Alzheimer’s disease. Explain what normal processes are disrupted in Alzheimer’s disease, and how this pathophysiology results in the symptoms observed.

Now, use pen and paper or digital drawing to create a two-panel image that illustrates the neuronal changes that underpin learning and memory, and then the consequences of the Alzheimer’s disease pathology on cognition. Consider the role of amyloid-beta and tau proteins in the pathophysiology of Alzheimer's disease. How do abnormalities in these proteins contribute to the development of AD, and what impact do these disruptions have on function and cognition?

[8 marks, 10 minutes]