It is recommended to estimate the pre-test likelihood using the Risk Factor-weighted Clinical Likelihood model

In individuals with a low (>5%–15%) pre-test likelihood, coronary artery calcium score (CACS) should be considered to reclassify subjects and to identify more individuals with very low (≤5%) CACS-weighted clinical likelihood.

Invasive coronary angiography is recommended for individuals with suspected CCS and a low pretest probability (>5-15%)

In individuals with a very low (≤5%) pre-test likelihood, coronary computed tomography angiography (CCTA) is recommended