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A 36-year-old man is required to attend a Pulmonary clinic as part of a contact investigation for a person who tested positive for tuberculosis. He works in a factory where he encounters a large number of unvaccinated persons among whom the disease has begun to spread. Since the man is properly vaccinated and his results are negative, this check is performed only a once. is a specific bacterium that is able to survive after phagocytosis inside macrophages. Once it is engulfed by macrophages, it starts to produce a protein called PtpA (protein tyrosine phosphatase A). These molecules knock out two different mechanisms that the macrophage needs to create the acidic environment necessary for bacteria to break down. As a result, the tuberculosis bacteria hide inside the macrophages and completely escape the attention of the immune system. When they multiply sufficiently, they escape the cell and invade other parts of the body. What should properly occur after phagocytosis and destruction of these bacteria inside the macrophage?
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