A 3-month-old male infant is brought to the pediatrician by his parents due to feeding difficulties and characteristic facial features. Upon examination, the infant displays downward-slanting palpebral fissures, colobomas of the lower eyelids, malar hypoplasia, and a prominent nose with a flat nasal bridge. Additionally, the infant has a small mandible (micrognathia) with a high-arched palate. These features are consistent with Treacher Collins syndrome (TCS).
Which of the following embryological processes is most directly implicated in the pathogenesis of this syndrome?

Question

A 3-month-old male infant is brought to the pediatrician by his parents due to feeding difficulties and characteristic facial features. Upon examination, the infant displays downward-slanting palpebral fissures, colobomas of the lower eyelids, malar hypoplasia, and a prominent nose with a flat nasal bridge. Additionally, the infant has a small mandible (micrognathia) with a high-arched palate. These features are consistent with Treacher Collins syndrome (TCS).  
 Which of the following embryological processes is most directly implicated in the pathogenesis of this syndrome?

Answer

Disruption of the paraxial mesoderm formation

Answer

Defective migration of neural crest cells

Answer

Defect in the closure of the neural tube

Answer

Abnormal migration of the endodermal cells

Crowdly

A 3-month-old male infant is brought to the pediatrician by his parents due to ...

Хочете миттєвий доступ до всіх перевірених відповідей на www.gmu-elc.com?