The dopamine hypothesis and

glutamate hypothesis are two major models explaining the neurochemical basis of

schizophrenia.

Critically

compare these two hypotheses,

including:

• The key neurochemical changes proposed in each

• The types of symptoms each hypothesis explains

  (positive, negative, cognitive)

• How current and emerging treatments align with

  these models

• Which hypothesis you think offers a better

  framework for future drug discovery, and why