The expansion of both CD4 and CD8 T cells is about equal to provide a targeted and specific response.

CD8 T cell expansion will outnumber CD4 T cell expansion due to the effector function of CTLs compared to T helper cells.

The pathogen epitopes that are presented to both the CD4 and CD8 T cells will be identical to enhance effector functions.

It is the role of the CD4 T cell once activated to then present antigen to naive CD8 T cells to drive activation and the generation of CTLs.