Question C3

Explain the link

between receptor interaction, the response measured in the study and the

potential anti-obesity effect of your chosen drug.

Question C2

Question C1

Question B3

List TWO advantages of

controlling a single cellular response through multiple pathways

Question B2

What can be concluded

from the data above? Based on the three ligands, EGF (E), Adrenaline (A) and

Cytokine (C), and the molecules measured, which ligand(s), receptor class(es)

and intracellular pathway(s) are involved in activating the transcription

factor HMBC in skin cells?

Question B1

Three molecules are

measured in addition to Phospho-HMBC. Describe the events that lead to the activation

of each of the receptors involved in activating each of the three molecules. In

your answer, include a description of how each of the three receptors activate

intracellular target molecules (you don’t need to explain the full

intracellular pathways however).

Question A3

Some of the enzymes

involved in the removal of nitrogen from the body are regulated via allosteric

regulation. Describe what is meant by allosteric regulation including the

consequence on enzymes regulated in this manner. 

Question A2

Glutamine has an

important role in metabolism. What relationship does glutamine have with

glutamate and

Question A1

From the data above,

what enzyme could the patient be deficient for? What is the role of this enzyme

and what is the significance of its deficiency?

Which of the following individuals is most likely to be in nitrogen balance?