Gene
therapy can be used to treat cases of defective genes of LDLR. Genetic material
either as DNA or m-RNA can be inserted into cells via in-vitro (in the lab/on
cell culture plates) or in-vivo (in the living organism directly).

Question

Answer

Electric pulse can be used to create pores in the cell membrane and
introduce DNA.

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Bacteriophages cannot be used as one of means of introducing genes in
recipient cells for gene therapy.

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If there are no non-coding sequences in the m-RNA, then spliceosomes
would be needed to allow for successful translation of LDLR.

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Translation of m-RNA with the correct codon sequence for the LDLR protein
(Ldlr mRNA) leads to the production of LDLR.

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When the Ldlr mRNA is inserted in-vivo in the mouse, plaque formation
happens since the LDLR isn’t formed.

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Gene therapy can be used to treat cases of defective genes of LDLR. Genetic mate...

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