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Shown below is a free energy diagram representing a generic reaction of a substrate (S) to give a product (P), in the absence and presence of an enzyme.
Specific points on the free energy diagram are labelled A-D.
Free energy differences are labelled by arrows 1-14 on the right with the following colour code:
[Note that a free energy difference is defined as the free energy of the destination (arrow head) minus the free energy of the origin (arrow tail)].
Which point represents the transition state of the enzyme-catalysed reaction?
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