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The following questions relate to the following pA2 values for a series of antagonists at serotonin (5-HT) receptor subtypes.
Which one of the following BEST represents the potency profile of Compound 02 at each receptor subtype?
Which one of the listed compounds shows the HIGHEST potency at 5-HT1d receptors?
5-HT3 receptor antagonists can be used to treat nausea, but can cause unwanted effects at 5-HT2 receptors on platelets. If you wanted to develop a new 5-HT3 antagonist that is unlikely to interact with 5-HT2 receptors, which one of the listed compounds would be the BEST choice?
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