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You are a clinician explaining Alzheimer’s disease progression to a patient’s f...

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You are a clinician explaining

Alzheimer’s disease progression to a patient’s family member.

Using plain language, describe what happens to the brain structurally and

chemically in AD and how this explains the patient’s:

  • Memory

    loss

  • Difficulty

    with speech or language

  • Confusion

    and personality changes

Your response should explain links between brain region damage (e.g.

hippocampus, cortex), cholinergic deficits, and hallmark pathology (plaques and

tangles).

[8 marks,

10 minutes]

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