G protein-coupled receptors (GPCRs) and tyrosine kinase receptors are two different families of transmembrane signalling molecules. Activation of each family of receptors initiates intracellular signalling events.
Which of the following features are shared by both of these receptor families and their signalling mechanisms?

Question

G protein-coupled receptors (GPCRs) and tyrosine kinase receptors are two different families of transmembrane signalling molecules. Activation of each family of receptors initiates intracellular signalling events. 
 Which of the following features are shared by  both  of these receptor families and their signalling mechanisms?

Answer

Signalling requires transport of molecules across the membrane.

Answer

Ligand binding to the extracellular side of the receptor causes a conformational change of the intracellular part of the receptor.

Answer

The cytoplasmic domain of each receptor undergoes autophosphorylation

Answer

The signal from receptor activation is amplified through a cascade of enzymatic or binding steps.

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G protein-coupled receptors (GPCRs) and tyrosine kinase receptors are two differ...

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