Mast cells are particularly important in innate immune responses because:

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Mast cells produce acute phase proteins and induce fever

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They have a role in adaptive responses as antigen-presenting cells and are targets of the effector components of adaptive responses

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They are capable of detecting infectious agents and initiating an acute inflammatory response through secretion of mediators (histamine, tryptase, chymase, and carboxypeptidas)

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They are capable of detecting infectious agents and initiating an acute inflammatory response through direct pathogen killing

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They are capable of detecting infectious agents and initiating an acute inflammatory response through production of IL-1 beta, IL-6, and IL-8 and IL-3

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Mast cells are particularly important in innate immune responses because:

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