The leading strand is synthesised in the same direction as the movement of the replication fork, and the lagging strand is synthesised in the opposite direction.

The leading strand is synthesised by adding nucleotides to the 3' end of the growing strand, and the lagging strand is synthesised by adding nucleotides to the 5' end.

The lagging strand is synthesised continuously, whereas the leading strand is synthesised in short fragments that are ultimately stitched together.

The leading strand is synthesised at twice the rate of the lagging strand.

Additional proofreading will occur

No replication fork will be formed

Replication will occur via RNA polymerase alone

Replication will require a DNA template from another source

primase

DNA polymerase

ligase

single-strand DNA binding proteins

The structures that hold two sister chromatids together.

Enzymes that elongate the DNA strand during replication.

The sites of origin of DNA replication.

The ends of linear chromosomes.

Prokaryotic chromosomes have histones, whereas eukaryotic chromosomes do not.

Prokaryotic chromosomes have a single origin of replication, whereas eukaryotic chromosomes have many.

The rate of elongation during DNA replication is slower in prokaryotes than in eukaryotes.

Prokaryotes produce Okazaki fragments during DNA replication, but eukaryotes do not.

Relieving strain in the DNA ahead of the replication fork caused by the untwisting of the double helix.

Elongating new DNA at a replication fork by adding nucleotides to the existing chain.

Reattaching the hydrogen bonds between the base pairs in the double helix.

Building RNA primers using the parental DNA strand as a template.

There would be an increase in the amount of DNA produced during replication.

The cell's DNA could not be packed into its nucleus.

Spindle fibres would not form during prophase.

Amplification of other genes would compensate for the lack of histones.

It synthesises RNA nucleotides to make a primer.

It joins Okazaki fragments together.

It unwinds the parental double helix.

It stabilises the unwound parental DNA.

leading strands and Okazaki fragments

lagging strands and Okazaki fragments

Okazaki fragments and RNA primers

leading strands and RNA primers

progresses away from the replication fork.

occurs in the 3′ → 5′ direction.

produces Okazaki fragments.

depends on the action of DNA polymerase.